Important Notice: MOTS-C and all products sold by Peptronic Labs are strictly for laboratory research and analytical purposes only. Not intended for human consumption, diagnostic, therapeutic, or veterinary use.
MOTS-C : Research Overview
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide encoded within the 12S ribosomal RNA gene. In recent laboratory research, it is recognized as a key regulator of metabolic homeostasis and mitochondrial function.
Its unique origin within the mitochondrial genome makes it a primary subject for studying the communication between mitochondria and the nucleus in metabolic signaling research.
Recent studies have shown that MOTS-C plays a crucial role in various physiological processes, including the regulation of energy expenditure and the modulation of inflammation, which are vital for understanding metabolic diseases.
This comprehensive understanding of MOTS-C is essential for ongoing MOTS-C : Research Overview.
Furthermore, the exploration of MOTS-C : Research Overview has the potential to reveal new therapeutic targets in metabolic health.
Mechanisms of Interest
Metabolic Regulation: MOTS-C is studied for its ability to activate AMPK pathways, influencing glucose uptake and fatty acid oxidation in laboratory models. For instance, experiments have demonstrated that the administration of MOTS-C can significantly enhance glucose uptake in skeletal muscle cells, mimicking the effects of physical exercise. This finding is particularly relevant in the context of insulin resistance and type 2 diabetes.
In the context of MOTS-C : Research Overview, it is crucial to analyze its impact on glucose metabolism and overall energy homeostasis.
MOTS-C : Research Overview highlights the importance of understanding how this peptide can mimic the benefits of exercise.
As part of the MOTS-C : Research Overview, studies emphasize the necessity of mitochondrial health in the aging process.
This exploration is crucial within the broader scope of MOTS-C : Research Overview as it delves into its role in glucose regulation.
MOTS-C : Research Overview continues to evolve as new findings emerge regarding its effects in metabolic disorders.
Exercise Mimetic Research: Studies examine MOTS-C as an exercise mimetic compound, observing its ability to replicate certain metabolic adaptations associated with physical activity in cellular models.
Researchers have found that MOTS-C can induce the expression of genes typically activated by exercise, such as those involved in mitochondrial biogenesis and oxidative phosphorylation.
This suggests potential therapeutic applications for MOTS-C in treating metabolic disorders related to sedentary lifestyles.
Mitochondrial Communication: Research focuses on how MOTS-C travels from mitochondria to the nucleus to regulate stress response genes and metabolic adaptation pathways.
Understanding this communication is critical, as it sheds light on how cells adapt to various stressors, including nutrient deprivation and oxidative stress.
Furthermore, the role of MOTS-C in maintaining mitochondrial health and preventing dysfunction is an emerging area of interest in aging research.
Insulin Sensitivity: Laboratory models examine MOTS-C’s influence on insulin signaling pathways and glucose metabolism regulation.
Increased insulin sensitivity is vital for metabolic health, and ongoing research aims to elucidate the mechanisms by which MOTS-C enhances this process.
Preliminary results indicate that MOTS-C may enhance insulin receptor signaling, leading to improved glucose homeostasis.
MOTS-C : Research Overview continues to evolve as new findings emerge regarding its effects in metabolic disorders.
Technical Specifications
Understanding the applications of MOTS-C : Research Overview is essential for developing effective therapeutic strategies.
Proper storage is necessary to maintain the efficacy of MOTS-C : Research Overview in scientific experiments.
Researchers must keep in mind the implications of MOTS-C : Research Overview when interpreting experimental results.
| Property | Details |
| Name | MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) |
| Amino Acid Sequence | M-R-W-Q-E-M-G-Y-I-F-Y-P-R-K-L-R |
| Chemical Formula | C101H152N28O22S2 |
| Molecular Weight | ~2174.6 g/mol |
| CAS Number | 1627580-64-6 |
MOTS-C : Research Overview serves as a critical framework for advancing our understanding of metabolic health.
Research Applications
MOTS-C is actively utilized in metabolic research examining mitochondrial signaling, AMPK activation, and exercise mimetic mechanisms. It is frequently studied alongside SLU-PP-332 in comparative exercise mimetic and metabolic activation research. Additionally, the role of MOTS-C in age-related metabolic decline is being explored, highlighting its potential in combating age-associated diseases.
Frequently Asked Questions
What is MOTS-C used for in research? MOTS-C is used in laboratory models to study mitochondrial-nuclear communication, AMPK pathway activation, metabolic homeostasis, and exercise mimetic mechanisms. Its applications extend to exploring therapeutic strategies for metabolic disorders, providing insights that could lead to new treatments.
How should MOTS-C be stored? Once prepared for laboratory use, stable storage conditions require 2–8°C, with research utility typically observed within 14–21 days. Adhering to these storage guidelines is crucial to ensure the stability and efficacy of MOTS-C during experiments.
What is the purity of Peptronic Labs MOTS-C? Peptronic Labs supplies MOTS-C at ≥99.0% purity verified by Reversed-Phase HPLC. This high level of purity is essential for reliable experimental outcomes, as contaminants can significantly affect biological assays.
Is MOTS-C legal in the UK? MOTS-C is legal to purchase and possess in the UK for legitimate laboratory research purposes. It is not approved for human consumption. Researchers must ensure compliance with all relevant regulations when handling and using MOTS-C in their studies.
Peptronic Labs supplies MOTS-C 10MG for laboratory research use. Frequently studied alongside SLU-PP-332 and NAD+ 500MG in mitochondrial and metabolic signaling research, these compounds provide a comprehensive toolkit for researchers investigating mitochondrial function and metabolic regulation. The ongoing collaboration between scientists using these compounds is paving the way for significant advancements in our understanding of cellular metabolism and its implications for health and disease.
| Resource | Description | Link |
|---|---|---|
| PubMed | Peer-reviewed literature on mitochondrial-derived peptides. | View Studies |
| PubChem | Molecular structure and chemical database. | View Data |
| ClinicalTrials.gov | Ongoing and past clinical investigations. | View Trials |
